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Side-by-side financial comparison of Amphastar Pharmaceuticals, Inc. (AMPH) and AVANOS MEDICAL, INC. (AVNS). Click either name above to swap in a different company.

Amphastar Pharmaceuticals, Inc. is the larger business by last-quarter revenue ($183.1M vs $180.9M, roughly 1.0× AVANOS MEDICAL, INC.). Amphastar Pharmaceuticals, Inc. runs the higher net margin — 13.3% vs -0.7%, a 14.1% gap on every dollar of revenue. On growth, AVANOS MEDICAL, INC. posted the faster year-over-year revenue change (0.7% vs -1.8%). Amphastar Pharmaceuticals, Inc. produced more free cash flow last quarter ($24.6M vs $21.3M). Over the past eight quarters, AVANOS MEDICAL, INC.'s revenue compounded faster (4.4% CAGR vs 3.2%).

Amphastar Pharmaceuticals is a publicly traded American speciality pharmaceutical company. It was incorporated in May 2004 and primarily develops, manufactures, and sells inhalation and intranasal products.

Avanos Medical, Inc. is a medical technology company making clinical medical devices. The company consists of two franchises – Pain Management and Chronic Care – that address reducing the use of opioids while helping patients recover faster and preventing infection.

AMPH vs AVNS — Head-to-Head

Bigger by revenue
AMPH
AMPH
1.0× larger
AMPH
$183.1M
$180.9M
AVNS
Growing faster (revenue YoY)
AVNS
AVNS
+2.6% gap
AVNS
0.7%
-1.8%
AMPH
Higher net margin
AMPH
AMPH
14.1% more per $
AMPH
13.3%
-0.7%
AVNS
More free cash flow
AMPH
AMPH
$3.3M more FCF
AMPH
$24.6M
$21.3M
AVNS
Faster 2-yr revenue CAGR
AVNS
AVNS
Annualised
AVNS
4.4%
3.2%
AMPH

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AMPH
AMPH
AVNS
AVNS
Revenue
$183.1M
$180.9M
Net Profit
$24.4M
$-1.3M
Gross Margin
46.8%
47.5%
Operating Margin
19.4%
1.4%
Net Margin
13.3%
-0.7%
Revenue YoY
-1.8%
0.7%
Net Profit YoY
-35.7%
99.7%
EPS (diluted)
$0.51
$-0.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMPH
AMPH
AVNS
AVNS
Q4 25
$183.1M
$180.9M
Q3 25
$191.8M
$177.8M
Q2 25
$174.4M
$175.0M
Q1 25
$170.5M
$167.5M
Q4 24
$186.5M
$179.6M
Q3 24
$191.2M
$170.4M
Q2 24
$182.4M
$171.7M
Q1 24
$171.8M
$166.1M
Net Profit
AMPH
AMPH
AVNS
AVNS
Q4 25
$24.4M
$-1.3M
Q3 25
$17.4M
$-1.4M
Q2 25
$31.0M
$-76.8M
Q1 25
$25.3M
$6.6M
Q4 24
$38.0M
$-397.3M
Q3 24
$40.4M
$4.3M
Q2 24
$37.9M
$1.8M
Q1 24
$43.2M
$-900.0K
Gross Margin
AMPH
AMPH
AVNS
AVNS
Q4 25
46.8%
47.5%
Q3 25
51.4%
48.4%
Q2 25
49.6%
52.6%
Q1 25
50.0%
53.6%
Q4 24
46.5%
54.6%
Q3 24
53.3%
54.5%
Q2 24
52.2%
55.7%
Q1 24
52.4%
57.1%
Operating Margin
AMPH
AMPH
AVNS
AVNS
Q4 25
19.4%
1.4%
Q3 25
13.2%
0.1%
Q2 25
24.2%
-42.6%
Q1 25
21.9%
6.1%
Q4 24
24.2%
-233.0%
Q3 24
29.8%
7.0%
Q2 24
30.3%
3.7%
Q1 24
27.9%
2.4%
Net Margin
AMPH
AMPH
AVNS
AVNS
Q4 25
13.3%
-0.7%
Q3 25
9.0%
-0.8%
Q2 25
17.8%
-43.9%
Q1 25
14.8%
3.9%
Q4 24
20.4%
-221.2%
Q3 24
21.1%
2.5%
Q2 24
20.8%
1.0%
Q1 24
25.1%
-0.5%
EPS (diluted)
AMPH
AMPH
AVNS
AVNS
Q4 25
$0.51
$-0.02
Q3 25
$0.37
$-0.03
Q2 25
$0.64
$-1.66
Q1 25
$0.51
$0.14
Q4 24
$0.74
$-8.64
Q3 24
$0.78
$0.09
Q2 24
$0.73
$0.04
Q1 24
$0.81
$-0.02

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMPH
AMPH
AVNS
AVNS
Cash + ST InvestmentsLiquidity on hand
$282.8M
$89.8M
Total DebtLower is stronger
$608.7M
$90.3M
Stockholders' EquityBook value
$788.8M
$778.2M
Total Assets
$1.6B
$1.1B
Debt / EquityLower = less leverage
0.77×
0.12×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMPH
AMPH
AVNS
AVNS
Q4 25
$282.8M
$89.8M
Q3 25
$276.2M
$70.5M
Q2 25
$231.8M
$90.3M
Q1 25
$236.9M
$97.0M
Q4 24
$221.6M
$107.7M
Q3 24
$250.5M
$89.0M
Q2 24
$217.8M
$92.2M
Q1 24
$289.6M
$75.8M
Total Debt
AMPH
AMPH
AVNS
AVNS
Q4 25
$608.7M
$90.3M
Q3 25
$608.6M
$93.4M
Q2 25
$607.7M
$95.7M
Q1 25
$603.9M
$98.0M
Q4 24
$601.6M
$125.3M
Q3 24
$596.4M
$152.6M
Q2 24
$586.9M
$164.9M
Q1 24
$594.0M
$167.2M
Stockholders' Equity
AMPH
AMPH
AVNS
AVNS
Q4 25
$788.8M
$778.2M
Q3 25
$776.7M
$778.0M
Q2 25
$757.5M
$776.3M
Q1 25
$751.3M
$839.4M
Q4 24
$732.3M
$828.5M
Q3 24
$727.7M
$1.2B
Q2 24
$713.3M
$1.2B
Q1 24
$672.4M
$1.2B
Total Assets
AMPH
AMPH
AVNS
AVNS
Q4 25
$1.6B
$1.1B
Q3 25
$1.7B
$1.1B
Q2 25
$1.6B
$1.0B
Q1 25
$1.6B
$1.1B
Q4 24
$1.6B
$1.2B
Q3 24
$1.5B
$1.7B
Q2 24
$1.5B
$1.7B
Q1 24
$1.6B
$1.7B
Debt / Equity
AMPH
AMPH
AVNS
AVNS
Q4 25
0.77×
0.12×
Q3 25
0.78×
0.12×
Q2 25
0.80×
0.12×
Q1 25
0.80×
0.12×
Q4 24
0.82×
0.15×
Q3 24
0.82×
0.12×
Q2 24
0.82×
0.13×
Q1 24
0.88×
0.14×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMPH
AMPH
AVNS
AVNS
Operating Cash FlowLast quarter
$32.9M
$28.2M
Free Cash FlowOCF − Capex
$24.6M
$21.3M
FCF MarginFCF / Revenue
13.4%
11.8%
Capex IntensityCapex / Revenue
4.5%
3.8%
Cash ConversionOCF / Net Profit
1.35×
TTM Free Cash FlowTrailing 4 quarters
$121.2M
$43.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMPH
AMPH
AVNS
AVNS
Q4 25
$32.9M
$28.2M
Q3 25
$52.6M
$14.0M
Q2 25
$35.6M
$6.8M
Q1 25
$35.1M
$25.7M
Q4 24
$29.0M
$57.9M
Q3 24
$60.0M
$23.0M
Q2 24
$69.1M
$27.8M
Q1 24
$55.3M
$-8.0M
Free Cash Flow
AMPH
AMPH
AVNS
AVNS
Q4 25
$24.6M
$21.3M
Q3 25
$47.2M
$7.0M
Q2 25
$25.0M
$-4.2M
Q1 25
$24.4M
$19.0M
Q4 24
$16.6M
$53.1M
Q3 24
$46.2M
$20.0M
Q2 24
$63.1M
$21.9M
Q1 24
$46.5M
$-12.1M
FCF Margin
AMPH
AMPH
AVNS
AVNS
Q4 25
13.4%
11.8%
Q3 25
24.6%
3.9%
Q2 25
14.3%
-2.4%
Q1 25
14.3%
11.3%
Q4 24
8.9%
29.6%
Q3 24
24.1%
11.7%
Q2 24
34.6%
12.8%
Q1 24
27.1%
-7.3%
Capex Intensity
AMPH
AMPH
AVNS
AVNS
Q4 25
4.5%
3.8%
Q3 25
2.8%
3.9%
Q2 25
6.1%
6.3%
Q1 25
6.3%
4.0%
Q4 24
6.7%
2.7%
Q3 24
7.2%
1.8%
Q2 24
3.3%
3.4%
Q1 24
5.1%
2.5%
Cash Conversion
AMPH
AMPH
AVNS
AVNS
Q4 25
1.35×
Q3 25
3.03×
Q2 25
1.15×
Q1 25
1.39×
3.89×
Q4 24
0.76×
Q3 24
1.48×
5.35×
Q2 24
1.82×
15.44×
Q1 24
1.28×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AMPH
AMPH

Other Products$62.4M34%
Baqsimi$46.7M26%
Primatenemist$27.9M15%
Epinephrine$17.1M9%
Lidocaine$14.9M8%
Glucagon$14.1M8%

AVNS
AVNS

Enteral Feeding$83.0M46%
Radiofrequency Ablation$36.9M20%
Neonate Solutions$32.1M18%
Surgical Pain And Recovery$24.7M14%
Corporate Other$4.2M2%

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