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Side-by-side financial comparison of COMMERCE BANCSHARES INC (CBSH) and Harmony Biosciences Holdings, Inc. (HRMY). Click either name above to swap in a different company.

COMMERCE BANCSHARES INC is the larger business by last-quarter revenue ($475.7M vs $243.8M, roughly 2.0× Harmony Biosciences Holdings, Inc.). COMMERCE BANCSHARES INC runs the higher net margin — 29.8% vs 9.2%, a 20.5% gap on every dollar of revenue. On growth, Harmony Biosciences Holdings, Inc. posted the faster year-over-year revenue change (21.1% vs 11.1%). Over the past eight quarters, Harmony Biosciences Holdings, Inc.'s revenue compounded faster (25.6% CAGR vs 7.1%).

Commerce Bancshares, Inc. is a regional bank holding company headquartered in Missouri, with principal offices in Kansas City and St. Louis. It is the corporate parent of Commerce Bank, which offers a diversified line of financial services, including business and personal banking, wealth management and investments through its affiliated companies.

Harmony Biosciences Holdings, Inc. is a commercial-stage biopharmaceutical company focused on developing and commercializing innovative therapies for rare neurological and central nervous system disorders. Its primary market is the United States, with its core product serving patients living with narcolepsy and other sleep-related CNS conditions across adult and pediatric segments.

CBSH vs HRMY — Head-to-Head

Bigger by revenue
CBSH
CBSH
2.0× larger
CBSH
$475.7M
$243.8M
HRMY
Growing faster (revenue YoY)
HRMY
HRMY
+10.0% gap
HRMY
21.1%
11.1%
CBSH
Higher net margin
CBSH
CBSH
20.5% more per $
CBSH
29.8%
9.2%
HRMY
Faster 2-yr revenue CAGR
HRMY
HRMY
Annualised
HRMY
25.6%
7.1%
CBSH

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
CBSH
CBSH
HRMY
HRMY
Revenue
$475.7M
$243.8M
Net Profit
$141.6M
$22.5M
Gross Margin
71.9%
Operating Margin
15.8%
Net Margin
29.8%
9.2%
Revenue YoY
11.1%
21.1%
Net Profit YoY
10.5%
-54.6%
EPS (diluted)
$0.96
$0.38

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CBSH
CBSH
HRMY
HRMY
Q1 26
$475.7M
Q4 25
$449.4M
$243.8M
Q3 25
$441.0M
$239.5M
Q2 25
$445.8M
$200.5M
Q1 25
$428.1M
$184.7M
Q4 24
$422.1M
$201.3M
Q3 24
$421.4M
$186.0M
Q2 24
$414.5M
$172.8M
Net Profit
CBSH
CBSH
HRMY
HRMY
Q1 26
$141.6M
Q4 25
$140.7M
$22.5M
Q3 25
$141.5M
$50.9M
Q2 25
$152.5M
$39.8M
Q1 25
$131.6M
$45.6M
Q4 24
$136.1M
$49.5M
Q3 24
$138.0M
$46.1M
Q2 24
$139.6M
$11.6M
Gross Margin
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
71.9%
Q3 25
75.1%
Q2 25
81.0%
Q1 25
82.7%
Q4 24
73.0%
Q3 24
77.0%
Q2 24
81.4%
Operating Margin
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
40.8%
15.8%
Q3 25
41.9%
27.3%
Q2 25
44.0%
24.0%
Q1 25
39.2%
30.4%
Q4 24
41.2%
27.7%
Q3 24
42.4%
33.2%
Q2 24
43.4%
12.4%
Net Margin
CBSH
CBSH
HRMY
HRMY
Q1 26
29.8%
Q4 25
31.3%
9.2%
Q3 25
32.1%
21.2%
Q2 25
34.2%
19.8%
Q1 25
30.7%
24.7%
Q4 24
32.2%
24.6%
Q3 24
32.8%
24.8%
Q2 24
33.7%
6.7%
EPS (diluted)
CBSH
CBSH
HRMY
HRMY
Q1 26
$0.96
Q4 25
$0.86
$0.38
Q3 25
$1.06
$0.87
Q2 25
$1.14
$0.68
Q1 25
$0.98
$0.78
Q4 24
$0.83
$0.85
Q3 24
$1.01
$0.79
Q2 24
$1.03
$0.20

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CBSH
CBSH
HRMY
HRMY
Cash + ST InvestmentsLiquidity on hand
$775.3M
Total DebtLower is stronger
$163.7M
Stockholders' EquityBook value
$4.3B
$870.2M
Total Assets
$35.7B
$1.3B
Debt / EquityLower = less leverage
0.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
$775.3M
Q3 25
$672.6M
Q2 25
$565.3M
Q1 25
$507.0M
Q4 24
$467.2M
Q3 24
$410.5M
Q2 24
$346.9M
Total Debt
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
$163.7M
Q3 25
$168.5M
Q2 25
$172.1M
Q1 25
$175.7M
Q4 24
$179.3M
Q3 24
$182.8M
Q2 24
$186.4M
Stockholders' Equity
CBSH
CBSH
HRMY
HRMY
Q1 26
$4.3B
Q4 25
$3.8B
$870.2M
Q3 25
$3.8B
$835.1M
Q2 25
$3.6B
$773.1M
Q1 25
$3.5B
$720.5M
Q4 24
$3.3B
$659.2M
Q3 24
$3.4B
$596.8M
Q2 24
$3.1B
$538.6M
Total Assets
CBSH
CBSH
HRMY
HRMY
Q1 26
$35.7B
Q4 25
$32.9B
$1.3B
Q3 25
$32.3B
$1.2B
Q2 25
$32.3B
$1.1B
Q1 25
$32.4B
$1.1B
Q4 24
$32.0B
$999.2M
Q3 24
$31.5B
$928.1M
Q2 24
$30.6B
$858.4M
Debt / Equity
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
0.19×
Q3 25
0.20×
Q2 25
0.22×
Q1 25
0.24×
Q4 24
0.27×
Q3 24
0.31×
Q2 24
0.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CBSH
CBSH
HRMY
HRMY
Operating Cash FlowLast quarter
$126.2M
Free Cash FlowOCF − Capex
$126.0M
FCF MarginFCF / Revenue
51.7%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
5.61×
TTM Free Cash FlowTrailing 4 quarters
$347.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
$645.1M
$126.2M
Q3 25
$129.0M
$108.7M
Q2 25
$111.2M
$79.3M
Q1 25
$138.6M
$34.0M
Q4 24
$577.9M
$75.6M
Q3 24
$431.7M
$70.5M
Q2 24
$147.4M
$42.6M
Free Cash Flow
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
$592.4M
$126.0M
Q3 25
$113.3M
$108.7M
Q2 25
$100.5M
$79.3M
Q1 25
$126.0M
$33.9M
Q4 24
$531.7M
$75.0M
Q3 24
$419.1M
$70.5M
Q2 24
$138.9M
$42.0M
FCF Margin
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
131.8%
51.7%
Q3 25
25.7%
45.4%
Q2 25
22.5%
39.6%
Q1 25
29.4%
18.3%
Q4 24
126.0%
37.3%
Q3 24
99.5%
37.9%
Q2 24
33.5%
24.3%
Capex Intensity
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
11.7%
0.0%
Q3 25
3.6%
0.0%
Q2 25
2.4%
0.0%
Q1 25
2.9%
0.1%
Q4 24
10.9%
0.3%
Q3 24
3.0%
0.0%
Q2 24
2.1%
0.4%
Cash Conversion
CBSH
CBSH
HRMY
HRMY
Q1 26
Q4 25
4.59×
5.61×
Q3 25
0.91×
2.14×
Q2 25
0.73×
1.99×
Q1 25
1.05×
0.75×
Q4 24
4.25×
1.53×
Q3 24
3.13×
1.53×
Q2 24
1.06×
3.68×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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