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Side-by-side financial comparison of COMERICA INC (CMA) and BeOne Medicines Ltd. (ONC). Click either name above to swap in a different company.

BeOne Medicines Ltd. is the larger business by last-quarter revenue ($1.5B vs $838.0M, roughly 1.8× COMERICA INC). COMERICA INC runs the higher net margin — 21.0% vs 4.4%, a 16.6% gap on every dollar of revenue. On growth, BeOne Medicines Ltd. posted the faster year-over-year revenue change (32.8% vs 3.3%). Over the past eight quarters, COMERICA INC's revenue compounded faster (108.9% CAGR vs 41.2%).

Comerica Incorporated is an American financial services company, headquartered in Dallas, Texas. It is the parent of Comerica Bank, a regional commercial bank with 413 branches in the U.S. states of Texas, Michigan, California, Florida and Arizona. Comerica is among the largest U.S. financial holding companies, with offices in a number of U.S. cities.

BeOne Medicines, formerly known as BeiGene, Ltd. is a multinational oncology company. It specializes in the development of drugs for cancer treatment.

CMA vs ONC — Head-to-Head

Bigger by revenue
ONC
ONC
1.8× larger
ONC
$1.5B
$838.0M
CMA
Growing faster (revenue YoY)
ONC
ONC
+29.5% gap
ONC
32.8%
3.3%
CMA
Higher net margin
CMA
CMA
16.6% more per $
CMA
21.0%
4.4%
ONC
Faster 2-yr revenue CAGR
CMA
CMA
Annualised
CMA
108.9%
41.2%
ONC

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
CMA
CMA
ONC
ONC
Revenue
$838.0M
$1.5B
Net Profit
$176.0M
$66.5M
Gross Margin
90.5%
Operating Margin
12.4%
Net Margin
21.0%
4.4%
Revenue YoY
3.3%
32.8%
Net Profit YoY
-4.3%
143.8%
EPS (diluted)
$1.35
$0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CMA
CMA
ONC
ONC
Q4 25
$1.5B
Q3 25
$838.0M
$1.4B
Q2 25
$849.0M
$1.3B
Q1 25
$829.0M
$1.1B
Q4 24
$825.0M
$1.1B
Q3 24
$811.0M
$1.0B
Q2 24
$824.0M
$929.2M
Q1 24
$784.0M
$751.7M
Net Profit
CMA
CMA
ONC
ONC
Q4 25
$66.5M
Q3 25
$176.0M
$124.8M
Q2 25
$199.0M
$94.3M
Q1 25
$172.0M
$1.3M
Q4 24
$170.0M
$-151.9M
Q3 24
$184.0M
$-121.3M
Q2 24
$206.0M
$-120.4M
Q1 24
$138.0M
$-251.2M
Gross Margin
CMA
CMA
ONC
ONC
Q4 25
90.5%
Q3 25
86.1%
Q2 25
87.5%
Q1 25
85.2%
Q4 24
85.8%
Q3 24
83.0%
Q2 24
85.1%
Q1 24
83.4%
Operating Margin
CMA
CMA
ONC
ONC
Q4 25
12.4%
Q3 25
11.5%
Q2 25
6.7%
Q1 25
1.0%
Q4 24
-7.0%
Q3 24
-12.0%
Q2 24
-11.5%
Q1 24
-34.8%
Net Margin
CMA
CMA
ONC
ONC
Q4 25
4.4%
Q3 25
21.0%
8.8%
Q2 25
23.4%
7.2%
Q1 25
20.7%
0.1%
Q4 24
20.6%
-13.5%
Q3 24
22.7%
-12.1%
Q2 24
25.0%
-13.0%
Q1 24
17.6%
-33.4%
EPS (diluted)
CMA
CMA
ONC
ONC
Q4 25
$0.05
Q3 25
$1.35
$0.08
Q2 25
$1.42
$0.06
Q1 25
$1.25
$0.00
Q4 24
$1.22
$-0.10
Q3 24
$1.33
$-0.09
Q2 24
$1.49
$-0.09
Q1 24
$0.98
$-0.19

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CMA
CMA
ONC
ONC
Cash + ST InvestmentsLiquidity on hand
$4.5B
Total DebtLower is stronger
$5.4B
$836.4M
Stockholders' EquityBook value
$7.4B
$4.4B
Total Assets
$77.4B
$8.2B
Debt / EquityLower = less leverage
0.73×
0.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CMA
CMA
ONC
ONC
Q4 25
$4.5B
Q3 25
$4.0B
Q2 25
$2.8B
Q1 25
$2.5B
Q4 24
$2.6B
Q3 24
$2.7B
Q2 24
$2.6B
Q1 24
$2.8B
Total Debt
CMA
CMA
ONC
ONC
Q4 25
$836.4M
Q3 25
$5.4B
Q2 25
$5.8B
Q1 25
$5.7B
Q4 24
$6.7B
Q3 24
$6.8B
Q2 24
$7.1B
Q1 24
$7.1B
Stockholders' Equity
CMA
CMA
ONC
ONC
Q4 25
$4.4B
Q3 25
$7.4B
$4.1B
Q2 25
$6.9B
$3.8B
Q1 25
$7.1B
$3.5B
Q4 24
$6.5B
$3.3B
Q3 24
$7.4B
$3.4B
Q2 24
$6.2B
$3.4B
Q1 24
$6.0B
$3.4B
Total Assets
CMA
CMA
ONC
ONC
Q4 25
$8.2B
Q3 25
$77.4B
$7.6B
Q2 25
$78.0B
$6.3B
Q1 25
$77.6B
$5.8B
Q4 24
$79.3B
$5.9B
Q3 24
$79.7B
$5.8B
Q2 24
$79.6B
$5.7B
Q1 24
$79.4B
$5.7B
Debt / Equity
CMA
CMA
ONC
ONC
Q4 25
0.19×
Q3 25
0.73×
Q2 25
0.84×
Q1 25
0.81×
Q4 24
1.02×
Q3 24
0.92×
Q2 24
1.15×
Q1 24
1.18×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CMA
CMA
ONC
ONC
Operating Cash FlowLast quarter
$-270.0M
$417.3M
Free Cash FlowOCF − Capex
$379.8M
FCF MarginFCF / Revenue
25.4%
Capex IntensityCapex / Revenue
2.5%
Cash ConversionOCF / Net Profit
-1.53×
6.28×
TTM Free Cash FlowTrailing 4 quarters
$941.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CMA
CMA
ONC
ONC
Q4 25
$417.3M
Q3 25
$-270.0M
$402.6M
Q2 25
$476.0M
$263.6M
Q1 25
$273.0M
$44.1M
Q4 24
$601.0M
$75.2M
Q3 24
$1.0B
$188.4M
Q2 24
$111.0M
$-95.6M
Q1 24
$-205.0M
$-308.6M
Free Cash Flow
CMA
CMA
ONC
ONC
Q4 25
$379.8M
Q3 25
$354.5M
Q2 25
$219.8M
Q1 25
$-12.3M
Q4 24
$-17.3M
Q3 24
$54.7M
Q2 24
$-205.5M
Q1 24
$-465.1M
FCF Margin
CMA
CMA
ONC
ONC
Q4 25
25.4%
Q3 25
25.1%
Q2 25
16.7%
Q1 25
-1.1%
Q4 24
-1.5%
Q3 24
5.5%
Q2 24
-22.1%
Q1 24
-61.9%
Capex Intensity
CMA
CMA
ONC
ONC
Q4 25
2.5%
Q3 25
3.4%
Q2 25
3.3%
Q1 25
5.0%
Q4 24
8.2%
Q3 24
13.3%
Q2 24
11.8%
Q1 24
20.8%
Cash Conversion
CMA
CMA
ONC
ONC
Q4 25
6.28×
Q3 25
-1.53×
3.22×
Q2 25
2.39×
2.79×
Q1 25
1.59×
34.71×
Q4 24
3.54×
Q3 24
5.70×
Q2 24
0.54×
Q1 24
-1.49×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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