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Side-by-side financial comparison of Esperion Therapeutics, Inc. (ESPR) and SIMMONS FIRST NATIONAL CORP (SFNC). Click either name above to swap in a different company.

SIMMONS FIRST NATIONAL CORP is the larger business by last-quarter revenue ($197.3M vs $168.4M, roughly 1.2× Esperion Therapeutics, Inc.). On growth, Esperion Therapeutics, Inc. posted the faster year-over-year revenue change (143.7% vs 19.6%). Over the past eight quarters, Esperion Therapeutics, Inc.'s revenue compounded faster (10.6% CAGR vs 0.6%).

Esperion Therapeutics, Inc. is a publicly traded American pharmaceutical company focused on the development of bempedoic acid, an orally available small molecule designed to lower elevated levels of LDL-C. The company is headquartered in Ann Arbor, Michigan.

Simmons Bank is a bank with operations in Arkansas, Kansas, Missouri, Oklahoma, Tennessee, and Texas. It is the primary subsidiary of Simmons First National Corporation, a bank holding company.

ESPR vs SFNC — Head-to-Head

Bigger by revenue
SFNC
SFNC
1.2× larger
SFNC
$197.3M
$168.4M
ESPR
Growing faster (revenue YoY)
ESPR
ESPR
+124.1% gap
ESPR
143.7%
19.6%
SFNC
Faster 2-yr revenue CAGR
ESPR
ESPR
Annualised
ESPR
10.6%
0.6%
SFNC

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ESPR
ESPR
SFNC
SFNC
Revenue
$168.4M
$197.3M
Net Profit
Gross Margin
Operating Margin
50.6%
Net Margin
Revenue YoY
143.7%
19.6%
Net Profit YoY
EPS (diluted)
$0.32
$0.36

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ESPR
ESPR
SFNC
SFNC
Q4 25
$168.4M
$197.3M
Q3 25
$87.3M
$186.7M
Q2 25
$82.4M
$214.2M
Q1 25
$65.0M
$209.6M
Q4 24
$69.1M
$208.5M
Q3 24
$51.6M
$174.8M
Q2 24
$73.8M
$197.2M
Q1 24
$137.7M
$195.1M
Net Profit
ESPR
ESPR
SFNC
SFNC
Q4 25
Q3 25
$-31.3M
$-562.8M
Q2 25
$-12.7M
$54.8M
Q1 25
$-40.5M
$32.4M
Q4 24
Q3 24
$-29.5M
$24.7M
Q2 24
$-61.9M
$40.8M
Q1 24
$61.0M
$38.9M
Operating Margin
ESPR
ESPR
SFNC
SFNC
Q4 25
50.6%
Q3 25
-11.4%
Q2 25
8.6%
Q1 25
-34.0%
Q4 24
-6.4%
Q3 24
-31.0%
Q2 24
3.5%
Q1 24
52.5%
Net Margin
ESPR
ESPR
SFNC
SFNC
Q4 25
Q3 25
-35.9%
-301.5%
Q2 25
-15.4%
25.6%
Q1 25
-62.2%
15.5%
Q4 24
Q3 24
-57.2%
14.1%
Q2 24
-83.9%
20.7%
Q1 24
44.3%
19.9%
EPS (diluted)
ESPR
ESPR
SFNC
SFNC
Q4 25
$0.32
$0.36
Q3 25
$-0.16
$-4.00
Q2 25
$-0.06
$0.43
Q1 25
$-0.21
$0.26
Q4 24
$-0.14
$0.38
Q3 24
$-0.15
$0.20
Q2 24
$-0.33
$0.32
Q1 24
$0.34
$0.31

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ESPR
ESPR
SFNC
SFNC
Cash + ST InvestmentsLiquidity on hand
$167.9M
Total DebtLower is stronger
$620.0M
Stockholders' EquityBook value
$-302.0M
$3.4B
Total Assets
$465.9M
$24.5B
Debt / EquityLower = less leverage
0.18×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ESPR
ESPR
SFNC
SFNC
Q4 25
$167.9M
Q3 25
$92.4M
Q2 25
$86.1M
Q1 25
$114.6M
Q4 24
$144.8M
Q3 24
$144.7M
Q2 24
$189.3M
Q1 24
$226.6M
Total Debt
ESPR
ESPR
SFNC
SFNC
Q4 25
$620.0M
Q3 25
$667.8M
Q2 25
$1.0B
Q1 25
$1.3B
Q4 24
$1.1B
Q3 24
$1.4B
Q2 24
$1.7B
Q1 24
$1.2B
Stockholders' Equity
ESPR
ESPR
SFNC
SFNC
Q4 25
$-302.0M
$3.4B
Q3 25
$-451.4M
$3.4B
Q2 25
$-433.5M
$3.5B
Q1 25
$-426.2M
$3.5B
Q4 24
$-388.7M
$3.5B
Q3 24
$-370.2M
$3.5B
Q2 24
$-344.2M
$3.5B
Q1 24
$-294.3M
$3.4B
Total Assets
ESPR
ESPR
SFNC
SFNC
Q4 25
$465.9M
$24.5B
Q3 25
$364.0M
$24.2B
Q2 25
$347.1M
$26.7B
Q1 25
$324.0M
$26.8B
Q4 24
$343.8M
$26.9B
Q3 24
$314.1M
$27.3B
Q2 24
$352.3M
$27.4B
Q1 24
$373.1M
$27.4B
Debt / Equity
ESPR
ESPR
SFNC
SFNC
Q4 25
0.18×
Q3 25
0.20×
Q2 25
0.28×
Q1 25
0.35×
Q4 24
0.32×
Q3 24
0.40×
Q2 24
0.50×
Q1 24
0.36×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ESPR
ESPR
SFNC
SFNC
Operating Cash FlowLast quarter
$45.2M
$449.5M
Free Cash FlowOCF − Capex
$411.4M
FCF MarginFCF / Revenue
208.5%
Capex IntensityCapex / Revenue
0.0%
19.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$717.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ESPR
ESPR
SFNC
SFNC
Q4 25
$45.2M
$449.5M
Q3 25
$-4.3M
$223.4M
Q2 25
$-31.4M
$77.6M
Q1 25
$-22.6M
$32.8M
Q4 24
$-35.0M
$425.9M
Q3 24
$-35.3M
$199.4M
Q2 24
$-7.2M
$86.1M
Q1 24
$53.8M
$57.6M
Free Cash Flow
ESPR
ESPR
SFNC
SFNC
Q4 25
$411.4M
Q3 25
$216.7M
Q2 25
$66.3M
Q1 25
$22.6M
Q4 24
$380.4M
Q3 24
$-35.5M
$187.7M
Q2 24
$-7.3M
$72.7M
Q1 24
$53.8M
$47.7M
FCF Margin
ESPR
ESPR
SFNC
SFNC
Q4 25
208.5%
Q3 25
116.1%
Q2 25
31.0%
Q1 25
10.8%
Q4 24
182.5%
Q3 24
-68.7%
107.4%
Q2 24
-9.9%
36.9%
Q1 24
39.0%
24.5%
Capex Intensity
ESPR
ESPR
SFNC
SFNC
Q4 25
0.0%
19.3%
Q3 25
0.0%
3.6%
Q2 25
0.0%
5.3%
Q1 25
0.0%
4.8%
Q4 24
0.0%
21.8%
Q3 24
0.3%
6.7%
Q2 24
0.1%
6.8%
Q1 24
0.1%
5.0%
Cash Conversion
ESPR
ESPR
SFNC
SFNC
Q4 25
Q3 25
Q2 25
1.42×
Q1 25
1.01×
Q4 24
Q3 24
8.06×
Q2 24
2.11×
Q1 24
0.88×
1.48×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ESPR
ESPR

Collaboration Revenue$124.7M74%
Products$43.7M26%

SFNC
SFNC

Segment breakdown not available.

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