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Side-by-side financial comparison of Opus Genetics, Inc. (IRD) and UNITED GUARDIAN INC (UG). Click either name above to swap in a different company.

Opus Genetics, Inc. is the larger business by last-quarter revenue ($3.9M vs $3.0M, roughly 1.3× UNITED GUARDIAN INC). On growth, UNITED GUARDIAN INC posted the faster year-over-year revenue change (19.6% vs -10.2%). Over the past eight quarters, Opus Genetics, Inc.'s revenue compounded faster (50.3% CAGR vs -4.6%).

Opus Genetics, Inc. is a clinical-stage biotechnology company specializing in the development of targeted gene therapies for inherited retinal diseases. It focuses on addressing unmet medical needs for patients living with rare, vision-threatening ocular conditions, with operations centered on advancing accessible therapeutic candidates for global rare disease patient populations.

The Guardian Life Insurance Company of America is one of the largest mutual life insurance companies in the world. Based in Manhattan, it has approximately 8,000 employees in the United States, and a network of over 3,000 financial representatives in more than 70 agencies nationwide. As of 2018, it ranks 239th on the Fortune 500 list of largest American corporations by revenue. In 2015, Guardian achieved the highest earnings in its 155-year history with $7.3 billion in capital and $1.5 billio...

IRD vs UG — Head-to-Head

Bigger by revenue
IRD
IRD
1.3× larger
IRD
$3.9M
$3.0M
UG
Growing faster (revenue YoY)
UG
UG
+29.7% gap
UG
19.6%
-10.2%
IRD
Faster 2-yr revenue CAGR
IRD
IRD
Annualised
IRD
50.3%
-4.6%
UG

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IRD
IRD
UG
UG
Revenue
$3.9M
$3.0M
Net Profit
Gross Margin
45.0%
Operating Margin
24.4%
Net Margin
Revenue YoY
-10.2%
19.6%
Net Profit YoY
53.0%
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRD
IRD
UG
UG
Q4 25
$3.9M
$3.0M
Q3 25
$3.1M
$2.3M
Q2 25
$2.9M
$2.8M
Q1 25
$4.4M
$2.5M
Q4 24
$4.3M
$2.5M
Q3 24
$3.9M
$3.1M
Q2 24
$1.1M
$3.4M
Q1 24
$1.7M
$3.3M
Net Profit
IRD
IRD
UG
UG
Q4 25
Q3 25
$-17.5M
$268.4K
Q2 25
$-7.4M
$626.8K
Q1 25
$-8.2M
$560.9K
Q4 24
Q3 24
$-7.5M
$865.5K
Q2 24
$-7.8M
$956.2K
Q1 24
$-7.1M
$925.4K
Gross Margin
IRD
IRD
UG
UG
Q4 25
45.0%
Q3 25
42.1%
Q2 25
52.8%
Q1 25
54.7%
Q4 24
51.7%
Q3 24
54.0%
Q2 24
54.0%
Q1 24
52.2%
Operating Margin
IRD
IRD
UG
UG
Q4 25
24.4%
Q3 25
-269.9%
9.5%
Q2 25
-309.0%
24.5%
Q1 25
-227.2%
24.6%
Q4 24
22.5%
Q3 24
-207.1%
31.0%
Q2 24
-748.9%
32.9%
Q1 24
-450.5%
31.5%
Net Margin
IRD
IRD
UG
UG
Q4 25
Q3 25
-566.9%
11.9%
Q2 25
-257.5%
22.1%
Q1 25
-187.5%
22.6%
Q4 24
Q3 24
-194.6%
28.3%
Q2 24
-698.3%
28.2%
Q1 24
-415.3%
28.4%
EPS (diluted)
IRD
IRD
UG
UG
Q4 25
Q3 25
$-0.25
Q2 25
$-0.12
Q1 25
$-0.24
Q4 24
Q3 24
$-0.29
Q2 24
$-0.30
Q1 24
$-0.29

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRD
IRD
UG
UG
Cash + ST InvestmentsLiquidity on hand
$45.1M
$8.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$15.3M
$11.2M
Total Assets
$50.2M
$13.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRD
IRD
UG
UG
Q4 25
$45.1M
$8.6M
Q3 25
$30.8M
$8.3M
Q2 25
$32.4M
$8.4M
Q1 25
$41.8M
$8.1M
Q4 24
$30.3M
$9.4M
Q3 24
$36.6M
$9.5M
Q2 24
$41.4M
$9.9M
Q1 24
$47.2M
$8.6M
Stockholders' Equity
IRD
IRD
UG
UG
Q4 25
$15.3M
$11.2M
Q3 25
$6.0M
$10.6M
Q2 25
$17.5M
$11.5M
Q1 25
$5.1M
$10.8M
Q4 24
$6.7M
$11.9M
Q3 24
$34.3M
$11.4M
Q2 24
$40.6M
$12.1M
Q1 24
$46.1M
$11.2M
Total Assets
IRD
IRD
UG
UG
Q4 25
$50.2M
$13.1M
Q3 25
$36.1M
$12.2M
Q2 25
$38.7M
$13.4M
Q1 25
$48.2M
$12.8M
Q4 24
$36.9M
$13.8M
Q3 24
$40.4M
$13.3M
Q2 24
$44.8M
$13.8M
Q1 24
$51.8M
$13.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRD
IRD
UG
UG
Operating Cash FlowLast quarter
$-35.3M
$330.5K
Free Cash FlowOCF − Capex
$308.0K
FCF MarginFCF / Revenue
10.4%
Capex IntensityCapex / Revenue
0.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$1.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRD
IRD
UG
UG
Q4 25
$-35.3M
$330.5K
Q3 25
$-6.2M
$1.0M
Q2 25
$-10.3M
$303.2K
Q1 25
$-9.0M
$322.1K
Q4 24
$-25.6M
$269.3K
Q3 24
$-5.1M
$1.2M
Q2 24
$-7.3M
$1.3M
Q1 24
$-5.7M
$644.1K
Free Cash Flow
IRD
IRD
UG
UG
Q4 25
$308.0K
Q3 25
$995.8K
Q2 25
$285.6K
Q1 25
$318.5K
Q4 24
$-45.9K
Q3 24
$1.2M
Q2 24
$1.3M
Q1 24
$622.2K
FCF Margin
IRD
IRD
UG
UG
Q4 25
10.4%
Q3 25
44.0%
Q2 25
10.1%
Q1 25
12.8%
Q4 24
-1.9%
Q3 24
39.2%
Q2 24
37.1%
Q1 24
19.1%
Capex Intensity
IRD
IRD
UG
UG
Q4 25
0.8%
Q3 25
0.7%
Q2 25
0.6%
Q1 25
0.1%
Q4 24
12.7%
Q3 24
1.0%
Q2 24
1.9%
Q1 24
0.7%
Cash Conversion
IRD
IRD
UG
UG
Q4 25
Q3 25
3.77×
Q2 25
0.48×
Q1 25
0.57×
Q4 24
Q3 24
1.42×
Q2 24
1.38×
Q1 24
0.70×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IRD
IRD

Segment breakdown not available.

UG
UG

Pharmaceuticals$1.6M53%
Other$1.4M47%

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