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Side-by-side financial comparison of Spero Therapeutics, Inc. (SPRO) and SWK Holdings Corp (SWKH). Click either name above to swap in a different company.
Spero Therapeutics, Inc. is the larger business by last-quarter revenue ($12.6M vs $8.7M, roughly 1.4× SWK Holdings Corp). On growth, Spero Therapeutics, Inc. posted the faster year-over-year revenue change (24080.8% vs -29.7%). Over the past eight quarters, Spero Therapeutics, Inc.'s revenue compounded faster (847.7% CAGR vs -12.5%).
SWK Holdings Corp is a specialty finance firm focused on the healthcare and life sciences sectors. It provides tailored financing solutions including royalty monetization, structured debt, and asset-backed lending to biotech, pharmaceutical, medical device and diagnostic companies, with its core market centered in North America.
SPRO vs SWKH — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $12.6M | $8.7M |
| Net Profit | $31.5M | $-19.4M |
| Gross Margin | — | — |
| Operating Margin | — | 9.9% |
| Net Margin | 250.7% | — |
| Revenue YoY | 24080.8% | -29.7% |
| Net Profit YoY | 250.9% | -430.2% |
| EPS (diluted) | $0.56 | $-1.59 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $12.6M | $8.7M | ||
| Q3 25 | $0 | $10.9M | ||
| Q2 25 | $0 | $10.1M | ||
| Q1 25 | $12.0K | $11.8M | ||
| Q4 24 | $52.0K | $12.4M | ||
| Q3 24 | $65.0K | $10.4M | ||
| Q2 24 | $114.0K | $10.8M | ||
| Q1 24 | $140.0K | $11.4M |
| Q4 25 | $31.5M | $-19.4M | ||
| Q3 25 | $-7.4M | $8.8M | ||
| Q2 25 | $-1.7M | $3.5M | ||
| Q1 25 | $-13.9M | $4.5M | ||
| Q4 24 | — | $5.9M | ||
| Q3 24 | $-17.1M | $3.5M | ||
| Q2 24 | $-17.9M | $3.7M | ||
| Q1 24 | $-12.7M | $468.0K |
| Q4 25 | — | 9.9% | ||
| Q3 25 | — | 61.3% | ||
| Q2 25 | — | 46.1% | ||
| Q1 25 | -122758.3% | 68.6% | ||
| Q4 24 | — | 44.7% | ||
| Q3 24 | -28604.6% | 39.2% | ||
| Q2 24 | -16720.2% | 8.3% | ||
| Q1 24 | -9987.1% | 9.5% |
| Q4 25 | 250.7% | — | ||
| Q3 25 | — | 80.7% | ||
| Q2 25 | — | 35.2% | ||
| Q1 25 | -115550.0% | 38.4% | ||
| Q4 24 | — | 47.5% | ||
| Q3 24 | -26380.0% | 33.3% | ||
| Q2 24 | -15668.4% | 33.9% | ||
| Q1 24 | -9049.3% | 4.1% |
| Q4 25 | $0.56 | $-1.59 | ||
| Q3 25 | $-0.13 | $0.72 | ||
| Q2 25 | $-0.03 | $0.29 | ||
| Q1 25 | $-0.25 | $0.37 | ||
| Q4 24 | — | $0.47 | ||
| Q3 24 | $-0.32 | $0.28 | ||
| Q2 24 | $-0.33 | $0.30 | ||
| Q1 24 | $-0.24 | $0.04 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $40.3M | $42.8M |
| Total DebtLower is stronger | — | $33.0M |
| Stockholders' EquityBook value | $59.0M | $235.1M |
| Total Assets | $68.9M | $272.4M |
| Debt / EquityLower = less leverage | — | 0.14× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $40.3M | $42.8M | ||
| Q3 25 | $48.6M | $10.2M | ||
| Q2 25 | $31.2M | $8.0M | ||
| Q1 25 | $48.9M | $29.8M | ||
| Q4 24 | $52.9M | $5.9M | ||
| Q3 24 | $76.3M | $17.2M | ||
| Q2 24 | $63.5M | $5.5M | ||
| Q1 24 | $82.3M | $5.5M |
| Q4 25 | — | $33.0M | ||
| Q3 25 | — | $33.0M | ||
| Q2 25 | — | $33.0M | ||
| Q1 25 | — | $33.0M | ||
| Q4 24 | — | $33.0M | ||
| Q3 24 | — | $33.0M | ||
| Q2 24 | — | $33.0M | ||
| Q1 24 | — | $33.0M |
| Q4 25 | $59.0M | $235.1M | ||
| Q3 25 | $26.5M | $254.2M | ||
| Q2 25 | $32.8M | $246.5M | ||
| Q1 25 | $33.8M | $292.7M | ||
| Q4 24 | $46.1M | $288.7M | ||
| Q3 24 | $65.5M | $283.4M | ||
| Q2 24 | $80.5M | $282.8M | ||
| Q1 24 | $96.2M | $279.9M |
| Q4 25 | $68.9M | $272.4M | ||
| Q3 25 | $54.2M | $289.4M | ||
| Q2 25 | $62.1M | $285.7M | ||
| Q1 25 | $77.7M | $331.3M | ||
| Q4 24 | $110.5M | $332.2M | ||
| Q3 24 | $135.2M | $321.3M | ||
| Q2 24 | $149.9M | $321.0M | ||
| Q1 24 | $167.7M | $322.0M |
| Q4 25 | — | 0.14× | ||
| Q3 25 | — | 0.13× | ||
| Q2 25 | — | 0.13× | ||
| Q1 25 | — | 0.11× | ||
| Q4 24 | — | 0.11× | ||
| Q3 24 | — | 0.12× | ||
| Q2 24 | — | 0.12× | ||
| Q1 24 | — | 0.12× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-8.4M | $27.3M |
| Free Cash FlowOCF − Capex | — | $26.8M |
| FCF MarginFCF / Revenue | — | 308.1% |
| Capex IntensityCapex / Revenue | — | 5.9% |
| Cash ConversionOCF / Net Profit | -0.26× | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $43.2M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-8.4M | $27.3M | ||
| Q3 25 | $17.4M | $906.0K | ||
| Q2 25 | $-17.7M | $7.8M | ||
| Q1 25 | $-4.0M | $8.3M | ||
| Q4 24 | $-23.4M | $23.0M | ||
| Q3 24 | $12.8M | $6.3M | ||
| Q2 24 | $-18.7M | $5.4M | ||
| Q1 24 | $5.9M | $4.4M |
| Q4 25 | — | $26.8M | ||
| Q3 25 | — | $557.0K | ||
| Q2 25 | — | $7.7M | ||
| Q1 25 | — | $8.2M | ||
| Q4 24 | — | $22.9M | ||
| Q3 24 | — | $6.3M | ||
| Q2 24 | — | $5.4M | ||
| Q1 24 | — | — |
| Q4 25 | — | 308.1% | ||
| Q3 25 | — | 5.1% | ||
| Q2 25 | — | 77.0% | ||
| Q1 25 | — | 69.1% | ||
| Q4 24 | — | 185.3% | ||
| Q3 24 | — | 60.4% | ||
| Q2 24 | — | 49.7% | ||
| Q1 24 | — | — |
| Q4 25 | — | 5.9% | ||
| Q3 25 | — | 3.2% | ||
| Q2 25 | — | 0.6% | ||
| Q1 25 | — | 0.8% | ||
| Q4 24 | — | 1.1% | ||
| Q3 24 | — | 0.3% | ||
| Q2 24 | — | 0.2% | ||
| Q1 24 | — | 0.0% |
| Q4 25 | -0.26× | — | ||
| Q3 25 | — | 0.10× | ||
| Q2 25 | — | 2.21× | ||
| Q1 25 | — | 1.82× | ||
| Q4 24 | — | 3.93× | ||
| Q3 24 | — | 1.82× | ||
| Q2 24 | — | 1.47× | ||
| Q1 24 | — | 9.47× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
SPRO
Segment breakdown not available.
SWKH
| Finance Receivables Segment | $8.4M | 96% |
| Other | $329.0K | 4% |
