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Side-by-side financial comparison of ACADIA PHARMACEUTICALS INC (ACAD) and Oportun Financial Corp (OPRT). Click either name above to swap in a different company.

ACADIA PHARMACEUTICALS INC is the larger business by last-quarter revenue ($284.0M vs $247.7M, roughly 1.1× Oportun Financial Corp). ACADIA PHARMACEUTICALS INC runs the higher net margin — 96.3% vs 1.4%, a 95.0% gap on every dollar of revenue. On growth, ACADIA PHARMACEUTICALS INC posted the faster year-over-year revenue change (9.4% vs -1.3%). Over the past eight quarters, ACADIA PHARMACEUTICALS INC's revenue compounded faster (17.5% CAGR vs -0.5%).

Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, San Diego, California.

Oportun Financial Corp is a US-based fintech firm that provides accessible, responsible financial services including personal loans, credit cards, and savings products to underserved low-to-moderate income consumers, many with limited or no credit history, leveraging proprietary AI underwriting to deliver fair terms while mitigating operational risk.

ACAD vs OPRT — Head-to-Head

Bigger by revenue
ACAD
ACAD
1.1× larger
ACAD
$284.0M
$247.7M
OPRT
Growing faster (revenue YoY)
ACAD
ACAD
+10.7% gap
ACAD
9.4%
-1.3%
OPRT
Higher net margin
ACAD
ACAD
95.0% more per $
ACAD
96.3%
1.4%
OPRT
Faster 2-yr revenue CAGR
ACAD
ACAD
Annualised
ACAD
17.5%
-0.5%
OPRT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ACAD
ACAD
OPRT
OPRT
Revenue
$284.0M
$247.7M
Net Profit
$273.6M
$3.4M
Gross Margin
90.8%
Operating Margin
6.1%
2.6%
Net Margin
96.3%
1.4%
Revenue YoY
9.4%
-1.3%
Net Profit YoY
90.3%
-61.0%
EPS (diluted)
$1.61
$0.07

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ACAD
ACAD
OPRT
OPRT
Q4 25
$284.0M
$247.7M
Q3 25
$278.6M
$238.7M
Q2 25
$264.6M
$234.3M
Q1 25
$244.3M
$235.9M
Q4 24
$259.6M
$250.9M
Q3 24
$250.4M
$250.0M
Q2 24
$242.0M
$250.4M
Q1 24
$205.8M
$250.5M
Net Profit
ACAD
ACAD
OPRT
OPRT
Q4 25
$273.6M
$3.4M
Q3 25
$71.8M
$5.2M
Q2 25
$26.7M
$6.9M
Q1 25
$19.0M
$9.8M
Q4 24
$143.7M
$8.7M
Q3 24
$32.8M
$-30.0M
Q2 24
$33.4M
$-31.0M
Q1 24
$16.6M
$-26.4M
Gross Margin
ACAD
ACAD
OPRT
OPRT
Q4 25
90.8%
Q3 25
92.2%
Q2 25
92.2%
Q1 25
91.7%
Q4 24
91.6%
Q3 24
92.5%
Q2 24
92.5%
Q1 24
88.8%
Operating Margin
ACAD
ACAD
OPRT
OPRT
Q4 25
6.1%
2.6%
Q3 25
12.8%
6.0%
Q2 25
12.2%
4.3%
Q1 25
7.9%
5.6%
Q4 24
59.1%
89.6%
Q3 24
12.6%
-15.8%
Q2 24
12.6%
-19.6%
Q1 24
7.4%
-12.2%
Net Margin
ACAD
ACAD
OPRT
OPRT
Q4 25
96.3%
1.4%
Q3 25
25.8%
2.2%
Q2 25
10.1%
2.9%
Q1 25
7.8%
4.1%
Q4 24
55.4%
200.1%
Q3 24
13.1%
-12.0%
Q2 24
13.8%
-12.4%
Q1 24
8.0%
-10.6%
EPS (diluted)
ACAD
ACAD
OPRT
OPRT
Q4 25
$1.61
$0.07
Q3 25
$0.42
$0.11
Q2 25
$0.16
$0.14
Q1 25
$0.11
$0.21
Q4 24
$0.86
$0.26
Q3 24
$0.20
$-0.75
Q2 24
$0.20
$-0.78
Q1 24
$0.10
$-0.68

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ACAD
ACAD
OPRT
OPRT
Cash + ST InvestmentsLiquidity on hand
$177.7M
$105.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$390.1M
Total Assets
$1.6B
$3.3B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ACAD
ACAD
OPRT
OPRT
Q4 25
$177.7M
$105.5M
Q3 25
$258.0M
$104.6M
Q2 25
$253.6M
$96.8M
Q1 25
$217.7M
$78.5M
Q4 24
$319.6M
$60.0M
Q3 24
$155.1M
$71.8M
Q2 24
$177.1M
$72.9M
Q1 24
$204.7M
$69.2M
Stockholders' Equity
ACAD
ACAD
OPRT
OPRT
Q4 25
$1.2B
$390.1M
Q3 25
$917.3M
$383.9M
Q2 25
$822.4M
$376.0M
Q1 25
$765.2M
$366.1M
Q4 24
$732.8M
$353.8M
Q3 24
$577.2M
$327.6M
Q2 24
$516.7M
$354.1M
Q1 24
$464.0M
$382.0M
Total Assets
ACAD
ACAD
OPRT
OPRT
Q4 25
$1.6B
$3.3B
Q3 25
$1.3B
$3.2B
Q2 25
$1.2B
$3.2B
Q1 25
$1.1B
$3.2B
Q4 24
$1.2B
$3.2B
Q3 24
$976.9M
$3.3B
Q2 24
$914.1M
$3.3B
Q1 24
$855.1M
$3.3B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ACAD
ACAD
OPRT
OPRT
Operating Cash FlowLast quarter
$-48.7M
$413.4M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
-0.18×
121.45×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ACAD
ACAD
OPRT
OPRT
Q4 25
$-48.7M
$413.4M
Q3 25
$74.3M
$99.0M
Q2 25
$64.0M
$104.5M
Q1 25
$20.3M
$101.0M
Q4 24
$40.4M
$393.5M
Q3 24
$63.2M
$108.5M
Q2 24
$25.0M
$107.7M
Q1 24
$29.1M
$85.9M
Free Cash Flow
ACAD
ACAD
OPRT
OPRT
Q4 25
Q3 25
$73.9M
Q2 25
Q1 25
Q4 24
Q3 24
$63.2M
Q2 24
Q1 24
FCF Margin
ACAD
ACAD
OPRT
OPRT
Q4 25
Q3 25
26.5%
Q2 25
Q1 25
Q4 24
Q3 24
25.2%
Q2 24
Q1 24
Capex Intensity
ACAD
ACAD
OPRT
OPRT
Q4 25
Q3 25
0.1%
Q2 25
Q1 25
Q4 24
Q3 24
0.0%
Q2 24
Q1 24
Cash Conversion
ACAD
ACAD
OPRT
OPRT
Q4 25
-0.18×
121.45×
Q3 25
1.03×
19.05×
Q2 25
2.40×
15.20×
Q1 25
1.07×
10.34×
Q4 24
0.28×
45.04×
Q3 24
1.93×
Q2 24
0.75×
Q1 24
1.76×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ACAD
ACAD

Nuplazid$174.4M61%
Daybue$109.6M39%

OPRT
OPRT

Segment breakdown not available.

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