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Side-by-side financial comparison of American Express (AXP) and Avidity Biosciences, Inc. (RNA). Click either name above to swap in a different company.

American Express is the larger business by last-quarter revenue ($18.9M vs $12.5M, roughly 1.5× Avidity Biosciences, Inc.). American Express runs the higher net margin — 15.7% vs -1398.3%, a 1414.0% gap on every dollar of revenue. On growth, Avidity Biosciences, Inc. posted the faster year-over-year revenue change (434.0% vs 11.4%). Over the past eight quarters, Avidity Biosciences, Inc.'s revenue compounded faster (138.5% CAGR vs -95.6%).

American Express Company, together with its subsidiaries, provides charge and credit payment card products, and travel-related services worldwide. The company operates through three segments: Global Consumer Services Group, Global Commercial Services, and Global Merchant and Network Services. Its products and services include payment and financing products; network services; accounts payable expense management products and services; and travel and lifestyle services. The company's products an...

Eli Lilly and Company, doing business as Lilly, is an American multinational pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by Eli Lilly, a pharmaceutical chemist and Union army veteran during the American Civil War for whom the company was later named.

AXP vs RNA — Head-to-Head

Bigger by revenue
AXP
AXP
1.5× larger
AXP
$18.9M
$12.5M
RNA
Growing faster (revenue YoY)
RNA
RNA
+422.6% gap
RNA
434.0%
11.4%
AXP
Higher net margin
AXP
AXP
1414.0% more per $
AXP
15.7%
-1398.3%
RNA
Faster 2-yr revenue CAGR
RNA
RNA
Annualised
RNA
138.5%
-95.6%
AXP

Income Statement — Q1 FY2026 vs Q3 FY2025

Metric
AXP
AXP
RNA
RNA
Revenue
$18.9M
$12.5M
Net Profit
$3.0M
$-174.4M
Gross Margin
Operating Margin
-1513.5%
Net Margin
15.7%
-1398.3%
Revenue YoY
11.4%
434.0%
Net Profit YoY
15.0%
-117.0%
EPS (diluted)
$-1.27

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXP
AXP
RNA
RNA
Q1 26
$18.9M
Q4 25
$10.9B
Q3 25
$10.4B
$12.5M
Q2 25
$10.3B
$3.8M
Q1 25
$9.6B
$1.6M
Q4 24
$10.0B
$3.0M
Q3 24
$9.7B
$2.3M
Q2 24
$9.8B
$2.0M
Net Profit
AXP
AXP
RNA
RNA
Q1 26
$3.0M
Q4 25
$2.5B
Q3 25
$2.9B
$-174.4M
Q2 25
$2.9B
$-157.3M
Q1 25
$2.6B
$-115.8M
Q4 24
$2.2B
$-102.3M
Q3 24
$2.5B
$-80.4M
Q2 24
$3.0B
$-70.8M
Operating Margin
AXP
AXP
RNA
RNA
Q1 26
Q4 25
28.2%
Q3 25
36.7%
-1513.5%
Q2 25
34.4%
-4448.7%
Q1 25
34.6%
-8360.9%
Q4 24
27.7%
-4069.6%
Q3 24
33.0%
-4200.9%
Q2 24
38.6%
-4040.4%
Net Margin
AXP
AXP
RNA
RNA
Q1 26
15.7%
Q4 25
22.5%
Q3 25
27.9%
-1398.3%
Q2 25
28.0%
-4089.3%
Q1 25
26.8%
-7360.0%
Q4 24
21.8%
-3439.5%
Q3 24
25.8%
-3441.7%
Q2 24
30.7%
-3461.8%
EPS (diluted)
AXP
AXP
RNA
RNA
Q1 26
Q4 25
$3.52
Q3 25
$4.14
$-1.27
Q2 25
$4.08
$-1.21
Q1 25
$3.64
$-0.90
Q4 24
$3.04
$-0.80
Q3 24
$3.49
$-0.65
Q2 24
$4.15
$-0.65

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXP
AXP
RNA
RNA
Cash + ST InvestmentsLiquidity on hand
$350.2M
Total DebtLower is stronger
$60.4M
Stockholders' EquityBook value
$34.0M
$1.9B
Total Assets
$308.9M
$2.1B
Debt / EquityLower = less leverage
1.78×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXP
AXP
RNA
RNA
Q1 26
Q4 25
$742.0M
Q3 25
$1.3B
$350.2M
Q2 25
$197.0M
$243.9M
Q1 25
$261.0M
$254.2M
Q4 24
$221.0M
$219.9M
Q3 24
$120.0M
$370.2M
Q2 24
$188.0M
$575.8M
Total Debt
AXP
AXP
RNA
RNA
Q1 26
$60.4M
Q4 25
$56.4B
Q3 25
$57.8B
Q2 25
$58.2B
Q1 25
$51.2B
Q4 24
$49.7B
Q3 24
$53.5B
Q2 24
$51.5B
Stockholders' Equity
AXP
AXP
RNA
RNA
Q1 26
$34.0M
Q4 25
$33.5B
Q3 25
$32.4B
$1.9B
Q2 25
$32.3B
$1.2B
Q1 25
$31.2B
$1.3B
Q4 24
$30.3B
$1.4B
Q3 24
$29.7B
$1.5B
Q2 24
$29.5B
$1.2B
Total Assets
AXP
AXP
RNA
RNA
Q1 26
$308.9M
Q4 25
$300.1B
Q3 25
$297.6B
$2.1B
Q2 25
$295.6B
$1.4B
Q1 25
$282.2B
$1.5B
Q4 24
$271.5B
$1.6B
Q3 24
$271.0B
$1.6B
Q2 24
$272.2B
$1.3B
Debt / Equity
AXP
AXP
RNA
RNA
Q1 26
1.78×
Q4 25
1.68×
Q3 25
1.78×
Q2 25
1.80×
Q1 25
1.64×
Q4 24
1.64×
Q3 24
1.80×
Q2 24
1.74×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXP
AXP
RNA
RNA
Operating Cash FlowLast quarter
$-156.2M
Free Cash FlowOCF − Capex
$-156.9M
FCF MarginFCF / Revenue
-1257.6%
Capex IntensityCapex / Revenue
5.7%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-592.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXP
AXP
RNA
RNA
Q1 26
Q4 25
$3.1B
Q3 25
$6.2B
$-156.2M
Q2 25
$4.4B
$-199.7M
Q1 25
$4.8B
$-124.8M
Q4 24
$5.8B
$-99.9M
Q3 24
$-1.8B
$-65.6M
Q2 24
$4.5B
$-65.0M
Free Cash Flow
AXP
AXP
RNA
RNA
Q1 26
Q4 25
$2.3B
Q3 25
$5.6B
$-156.9M
Q2 25
$3.7B
$-203.0M
Q1 25
$4.3B
$-128.6M
Q4 24
$5.3B
$-103.8M
Q3 24
$-2.3B
$-67.3M
Q2 24
$4.0B
$-65.5M
FCF Margin
AXP
AXP
RNA
RNA
Q1 26
Q4 25
21.4%
Q3 25
53.6%
-1257.6%
Q2 25
36.3%
-5277.1%
Q1 25
45.0%
-8174.3%
Q4 24
53.1%
-3491.0%
Q3 24
-23.3%
-2881.8%
Q2 24
40.4%
-3204.6%
Capex Intensity
AXP
AXP
RNA
RNA
Q1 26
Q4 25
6.6%
Q3 25
6.3%
5.7%
Q2 25
6.0%
86.9%
Q1 25
4.5%
238.6%
Q4 24
5.0%
131.7%
Q3 24
4.7%
72.9%
Q2 24
5.8%
26.0%
Cash Conversion
AXP
AXP
RNA
RNA
Q1 26
Q4 25
1.25×
Q3 25
2.15×
Q2 25
1.51×
Q1 25
1.84×
Q4 24
2.66×
Q3 24
-0.72×
Q2 24
1.50×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXP
AXP

Discount revenue$9.5M50%
Other$8.9M47%
Deposits with banks and other$512.0K3%

RNA
RNA

Segment breakdown not available.

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