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Side-by-side financial comparison of JBG SMITH Properties (JBGS) and Protagonist Therapeutics, Inc (PTGX). Click either name above to swap in a different company.

Protagonist Therapeutics, Inc is the larger business by last-quarter revenue ($170.6M vs $127.6M, roughly 1.3× JBG SMITH Properties). Protagonist Therapeutics, Inc runs the higher net margin — 77.2% vs -35.7%, a 112.9% gap on every dollar of revenue. On growth, Protagonist Therapeutics, Inc posted the faster year-over-year revenue change (184.4% vs -2.5%).

JBG SMITH Properties is a publicly traded real estate investment trust based in Bethesda, Maryland.

Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel peptide-based targeted therapies for unmet medical needs, primarily covering gastrointestinal disorders, inflammatory diseases and rare disease indications. Its lead product candidates target inflammatory bowel disease and other chronic immune-related conditions, with operations spanning global R&D and partnership collaborations.

JBGS vs PTGX — Head-to-Head

Bigger by revenue
PTGX
PTGX
1.3× larger
PTGX
$170.6M
$127.6M
JBGS
Growing faster (revenue YoY)
PTGX
PTGX
+186.9% gap
PTGX
184.4%
-2.5%
JBGS
Higher net margin
PTGX
PTGX
112.9% more per $
PTGX
77.2%
-35.7%
JBGS

Income Statement — Q4 FY2025 vs Q4 FY2024

Metric
JBGS
JBGS
PTGX
PTGX
Revenue
$127.6M
$170.6M
Net Profit
$-45.5M
$131.7M
Gross Margin
Operating Margin
-47.5%
74.3%
Net Margin
-35.7%
77.2%
Revenue YoY
-2.5%
184.4%
Net Profit YoY
24.0%
381.7%
EPS (diluted)
$-0.76
$2.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
JBGS
JBGS
PTGX
PTGX
Q4 25
$127.6M
Q3 25
$123.9M
Q2 25
$126.5M
Q1 25
$120.7M
Q4 24
$130.8M
$170.6M
Q3 24
$136.0M
Q2 24
$135.3M
Q1 24
$145.2M
$255.0M
Net Profit
JBGS
JBGS
PTGX
PTGX
Q4 25
$-45.5M
Q3 25
$-28.6M
Q2 25
$-19.2M
Q1 25
$-45.7M
Q4 24
$-59.9M
$131.7M
Q3 24
$-27.0M
Q2 24
$-24.4M
Q1 24
$-32.3M
$207.3M
Operating Margin
JBGS
JBGS
PTGX
PTGX
Q4 25
-47.5%
Q3 25
-27.5%
Q2 25
-18.4%
Q1 25
-44.7%
Q4 24
-53.6%
74.3%
Q3 24
-22.4%
Q2 24
-24.3%
Q1 24
-30.1%
80.9%
Net Margin
JBGS
JBGS
PTGX
PTGX
Q4 25
-35.7%
Q3 25
-23.1%
Q2 25
-15.2%
Q1 25
-37.9%
Q4 24
-45.8%
77.2%
Q3 24
-19.8%
Q2 24
-18.0%
Q1 24
-22.2%
81.3%
EPS (diluted)
JBGS
JBGS
PTGX
PTGX
Q4 25
$-0.76
Q3 25
$-0.48
Q2 25
$-0.29
Q1 25
$-0.56
Q4 24
$-0.70
$2.01
Q3 24
$-0.32
Q2 24
$-0.27
Q1 24
$-0.36
$3.26

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
JBGS
JBGS
PTGX
PTGX
Cash + ST InvestmentsLiquidity on hand
$75.3M
$418.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$675.3M
Total Assets
$4.4B
$744.7M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
JBGS
JBGS
PTGX
PTGX
Q4 25
$75.3M
Q3 25
$64.4M
Q2 25
$61.4M
Q1 25
$81.3M
Q4 24
$145.8M
$418.9M
Q3 24
$137.0M
Q2 24
$163.5M
Q1 24
$220.5M
$322.6M
Stockholders' Equity
JBGS
JBGS
PTGX
PTGX
Q4 25
$1.2B
Q3 25
$1.2B
Q2 25
$1.3B
Q1 25
$1.6B
Q4 24
$1.8B
$675.3M
Q3 24
$1.9B
Q2 24
$2.0B
Q1 24
$2.1B
$560.4M
Total Assets
JBGS
JBGS
PTGX
PTGX
Q4 25
$4.4B
Q3 25
$4.4B
Q2 25
$4.5B
Q1 25
$4.7B
Q4 24
$5.0B
$744.7M
Q3 24
$5.2B
Q2 24
$5.3B
Q1 24
$5.4B
$629.3M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
JBGS
JBGS
PTGX
PTGX
Operating Cash FlowLast quarter
$73.3M
$184.2M
Free Cash FlowOCF − Capex
$182.8M
FCF MarginFCF / Revenue
107.1%
Capex IntensityCapex / Revenue
0.8%
Cash ConversionOCF / Net Profit
1.40×
TTM Free Cash FlowTrailing 4 quarters
$101.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
JBGS
JBGS
PTGX
PTGX
Q4 25
$73.3M
Q3 25
$8.9M
Q2 25
$18.8M
Q1 25
$12.9M
Q4 24
$129.4M
$184.2M
Q3 24
$26.4M
Q2 24
$23.8M
Q1 24
$37.0M
$-27.4M
Free Cash Flow
JBGS
JBGS
PTGX
PTGX
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
$182.8M
Q3 24
Q2 24
Q1 24
$-27.7M
FCF Margin
JBGS
JBGS
PTGX
PTGX
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
107.1%
Q3 24
Q2 24
Q1 24
-10.9%
Capex Intensity
JBGS
JBGS
PTGX
PTGX
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
0.8%
Q3 24
Q2 24
Q1 24
0.1%
Cash Conversion
JBGS
JBGS
PTGX
PTGX
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
1.40×
Q3 24
Q2 24
Q1 24
-0.13×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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