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Side-by-side financial comparison of IONIS PHARMACEUTICALS INC (IONS) and Westrock Coffee Co (WEST). Click either name above to swap in a different company.

Westrock Coffee Co is the larger business by last-quarter revenue ($339.5M vs $203.3M, roughly 1.7× IONIS PHARMACEUTICALS INC). Westrock Coffee Co runs the higher net margin — -6.6% vs -112.8%, a 106.2% gap on every dollar of revenue. On growth, Westrock Coffee Co posted the faster year-over-year revenue change (48.3% vs -10.3%). Westrock Coffee Co produced more free cash flow last quarter ($27.8M vs $-159.0M). Over the past eight quarters, Westrock Coffee Co's revenue compounded faster (32.8% CAGR vs 30.4%).

Ionis Pharmaceuticals, Inc. is a biotechnology company that specializes in discovering and developing antisense therapy, as well as RNA interference and CRISPR therapeutics. The company was founded in 1989 is based in Carlsbad, California. The company was previously known as Isis Pharmaceuticals until December 2015.

Westrock Coffee Co is a global integrated coffee, tea and functional beverage solutions provider. It sources, roasts, manufactures and distributes coffee products, ready-to-drink beverages and custom formulations for retail, foodservice and commercial clients across North America and other key markets.

IONS vs WEST — Head-to-Head

Bigger by revenue
WEST
WEST
1.7× larger
WEST
$339.5M
$203.3M
IONS
Growing faster (revenue YoY)
WEST
WEST
+58.5% gap
WEST
48.3%
-10.3%
IONS
Higher net margin
WEST
WEST
106.2% more per $
WEST
-6.6%
-112.8%
IONS
More free cash flow
WEST
WEST
$186.8M more FCF
WEST
$27.8M
$-159.0M
IONS
Faster 2-yr revenue CAGR
WEST
WEST
Annualised
WEST
32.8%
30.4%
IONS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IONS
IONS
WEST
WEST
Revenue
$203.3M
$339.5M
Net Profit
$-229.4M
$-22.6M
Gross Margin
96.1%
11.5%
Operating Margin
-105.5%
-2.6%
Net Margin
-112.8%
-6.6%
Revenue YoY
-10.3%
48.3%
Net Profit YoY
-119.8%
8.3%
EPS (diluted)
$-1.35
$-0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IONS
IONS
WEST
WEST
Q4 25
$203.3M
$339.5M
Q3 25
$156.7M
$354.8M
Q2 25
$452.0M
$280.9M
Q1 25
$131.6M
$213.8M
Q4 24
$226.6M
$229.0M
Q3 24
$133.8M
$220.9M
Q2 24
$225.3M
$208.4M
Q1 24
$119.5M
$192.5M
Net Profit
IONS
IONS
WEST
WEST
Q4 25
$-229.4M
$-22.6M
Q3 25
$-128.6M
$-19.1M
Q2 25
$123.6M
$-21.6M
Q1 25
$-146.9M
$-27.2M
Q4 24
$-104.3M
$-24.6M
Q3 24
$-140.5M
$-14.3M
Q2 24
$-66.3M
$-17.8M
Q1 24
$-142.8M
$-23.7M
Gross Margin
IONS
IONS
WEST
WEST
Q4 25
96.1%
11.5%
Q3 25
98.5%
11.7%
Q2 25
99.1%
14.7%
Q1 25
98.9%
13.6%
Q4 24
98.3%
16.6%
Q3 24
99.2%
16.8%
Q2 24
98.2%
19.9%
Q1 24
98.2%
19.4%
Operating Margin
IONS
IONS
WEST
WEST
Q4 25
-105.5%
-2.6%
Q3 25
-102.2%
-2.4%
Q2 25
30.9%
-5.3%
Q1 25
-111.6%
-6.1%
Q4 24
-48.9%
-4.3%
Q3 24
-111.1%
-5.8%
Q2 24
-29.3%
-7.9%
Q1 24
-125.1%
-5.3%
Net Margin
IONS
IONS
WEST
WEST
Q4 25
-112.8%
-6.6%
Q3 25
-82.1%
-5.4%
Q2 25
27.3%
-7.7%
Q1 25
-111.6%
-12.7%
Q4 24
-46.1%
-10.7%
Q3 24
-105.0%
-6.5%
Q2 24
-29.4%
-8.5%
Q1 24
-119.5%
-12.3%
EPS (diluted)
IONS
IONS
WEST
WEST
Q4 25
$-1.35
$-0.22
Q3 25
$-0.80
$-0.20
Q2 25
$0.70
$-0.23
Q1 25
$-0.93
$-0.29
Q4 24
$-0.66
$-0.26
Q3 24
$-0.95
$-0.16
Q2 24
$-0.45
$-0.20
Q1 24
$-0.98
$-0.27

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IONS
IONS
WEST
WEST
Cash + ST InvestmentsLiquidity on hand
$2.7B
$49.9M
Total DebtLower is stronger
$1.8B
$444.1M
Stockholders' EquityBook value
$489.1M
$-1.9M
Total Assets
$3.5B
$1.2B
Debt / EquityLower = less leverage
3.71×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IONS
IONS
WEST
WEST
Q4 25
$2.7B
$49.9M
Q3 25
$2.2B
$34.0M
Q2 25
$2.3B
$44.0M
Q1 25
$2.1B
$33.1M
Q4 24
$2.3B
$26.2M
Q3 24
$2.5B
$22.4M
Q2 24
$2.1B
$24.3M
Q1 24
$2.2B
$12.6M
Total Debt
IONS
IONS
WEST
WEST
Q4 25
$1.8B
$444.1M
Q3 25
Q2 25
Q1 25
Q4 24
$1.3B
$393.1M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
IONS
IONS
WEST
WEST
Q4 25
$489.1M
$-1.9M
Q3 25
$618.0M
$11.4M
Q2 25
$631.7M
$18.2M
Q1 25
$475.7M
$71.4M
Q4 24
$588.4M
$97.5M
Q3 24
$662.5M
$110.3M
Q2 24
$263.7M
$81.5M
Q1 24
$296.5M
$91.7M
Total Assets
IONS
IONS
WEST
WEST
Q4 25
$3.5B
$1.2B
Q3 25
$3.0B
$1.2B
Q2 25
$3.0B
$1.2B
Q1 25
$2.8B
$1.1B
Q4 24
$3.0B
$1.1B
Q3 24
$3.1B
$1.1B
Q2 24
$2.7B
$1.1B
Q1 24
$2.8B
$983.3M
Debt / Equity
IONS
IONS
WEST
WEST
Q4 25
3.71×
Q3 25
Q2 25
Q1 25
Q4 24
2.13×
4.03×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IONS
IONS
WEST
WEST
Operating Cash FlowLast quarter
$-137.7M
$36.7M
Free Cash FlowOCF − Capex
$-159.0M
$27.8M
FCF MarginFCF / Revenue
-78.2%
8.2%
Capex IntensityCapex / Revenue
10.5%
2.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-320.0M
$-107.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IONS
IONS
WEST
WEST
Q4 25
$-137.7M
$36.7M
Q3 25
$-131.4M
$-26.6M
Q2 25
$151.3M
$-7.0M
Q1 25
$-150.8M
$-22.1M
Q4 24
$-116.1M
$2.8M
Q3 24
$-115.0M
$-332.0K
Q2 24
$-119.9M
$-23.7M
Q1 24
$-149.9M
$8.0M
Free Cash Flow
IONS
IONS
WEST
WEST
Q4 25
$-159.0M
$27.8M
Q3 25
$-136.7M
$-44.7M
Q2 25
$139.0M
$-27.5M
Q1 25
$-163.4M
$-63.4M
Q4 24
$-141.6M
$-15.4M
Q3 24
$-124.0M
$-36.7M
Q2 24
$-126.1M
$-59.9M
Q1 24
$-154.4M
$-60.9M
FCF Margin
IONS
IONS
WEST
WEST
Q4 25
-78.2%
8.2%
Q3 25
-87.2%
-12.6%
Q2 25
30.8%
-9.8%
Q1 25
-124.1%
-29.7%
Q4 24
-62.5%
-6.7%
Q3 24
-92.7%
-16.6%
Q2 24
-56.0%
-28.7%
Q1 24
-129.2%
-31.7%
Capex Intensity
IONS
IONS
WEST
WEST
Q4 25
10.5%
2.6%
Q3 25
3.4%
5.1%
Q2 25
2.7%
7.3%
Q1 25
9.6%
19.3%
Q4 24
11.3%
7.9%
Q3 24
6.8%
16.5%
Q2 24
2.8%
17.4%
Q1 24
3.8%
35.8%
Cash Conversion
IONS
IONS
WEST
WEST
Q4 25
Q3 25
Q2 25
1.22×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IONS
IONS

Products$58.0M29%
Spinraza Royalties$54.0M27%
Collaborative Agreement Revenue$52.4M26%
Wainus Royalties$16.0M8%
Wainua Joint Development Revenue$9.6M5%
Other Commercial$7.6M4%
Other Royalties$5.7M3%

WEST
WEST

Coffee And Tea$202.6M60%
Flavors Extracts And Ingredients$69.6M21%
Sustainable Sourcing And Traceability Segments$66.9M20%

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